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适度且规律的饮酒者,心脏病风险更低

2020-03-01 23:03

Conclusions

英国政府目前的建议是:男性每天饮酒不宜超过三至四个酒精单位,每周饮酒量应低于21个酒精单位;女性每天饮酒不宜超过两至三个酒精单位,每周饮酒量应低于14个酒精单位。

为了研究冠心病和长期饮酒行为之间的关系,研究者对6个研究中关于自我报告每周饮酒量的前瞻性纵向数据进行了分析,这6个研究中有5个来自英国,1个来自法国,数据中包括十年间的饮酒量和冠心病的相关信息。

报道引述英国政府内部专家的话称,红酒并不像大家此前认为的那样对健康有益,事实情况恰恰相反。这些专家正打算修订英国有关酒精摄入量的指导标准。

数字识别码:10.1186/s12916-018-1123-6

Under the new guidelines the gender difference will be thrown out and drinkers will be to keep off the booze for at least two days a week in order to allow their livers to recover.

生活方式上的变化可能还与研究者观察到的不同年龄组之间的风险差异有关。

A source said: "The report will send a clear signal that the dangers of drinking are far more than previously thought."

Methods

图片 1

Results

伦敦大学学院近期的一项研究显示,病人戒酒四周后,其肝功能、血压和胆固醇水平都有所好转;而且,病人患糖尿病和肝脏疾病的风险也降低了。

ONeill博士说:在人群级别的研究中,重度饮酒者的样本数量往往都不足,因此虽然我们的研究显示重度饮酒者的冠心病发病率并不算高,但这一结果的解读必须非常谨慎,毕竟我们已经知道重度的酒精摄入会引起很多健康问题。

而新的饮酒指南则认为:无论男女,饮酒者每周至少要有两天远离酒精, 使受伤的肝脏得以恢复。

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据英国《太阳报》报道,这份必将影响深远的报告源自首席医疗官莎莉?戴维斯女爵。该报告将彻底推翻人们长期以来秉持的一个观念——适度饮红酒可降低患上癌症、心脏病和失忆症的风险。

Compared to consistently moderate drinkers (males: 1168 g ethanol/week; females: 1112 g ethanol/week), inconsistently moderate drinkers had a significantly greater risk of incident CHD [hazard ratio (HR)=1.18, 95% confidence interval (CI)=1.021.37]. An elevated risk of incident CHD was also found for former drinkers (HR=1.31, 95% CI=1.131.52) and consistent non-drinkers (HR=1.47, 95% CI=1.211.78), although, after sex stratification, the latter effect was only evident for females. When examining fatal CHD outcomes alone, only former drinkers had a significantly elevated risk, though hazard ratios for consistent non-drinkers were near identical. No evidence of elevated CHD risk was found for consistently heavy drinkers, and a weak association with fatal CHD for inconsistently heavy drinkers was attenuated following adjustment for confounding factors.

A recent study by University College London found patients who gave up for four weeks saw benefits for their liver function, blood pressure and cholesterol levels and were also at lower risk of developing diabetes and liver disease.

图片 2

In a u-turn, Government experts have dismissed the supposed health benefits of wine and are set to rewrite the rule book on the nation’s alcohol consumption, according to reports.

Studies have shown that alcohol intake trajectories differ in their associations with biomarkers of cardiovascular functioning, but it remains unclear if they also differ in their relationship to actual coronary heart disease (CHD) incidence. Using multiple longitudinal cohort studies, we evaluated the association between long-term alcohol consumption trajectories and CHD.

It says the same health benefits can be more easily achieved with exercise and healthy eating.

由伦敦大学学院和剑桥大学领衔的一个研究团队发现,在为期10年的时间里,与那些遵循英国适度饮酒指南规律饮酒的人相比,适度但不规律饮酒者、曾经饮酒但已经戒酒者和自我报告中从不饮酒者罹患冠心病的风险更高,不过符合这一规律的不饮酒者仅限于女性。

In the first overhaul of alcohol guidelines for two decades, doctors will reportedly warn that there is no "safe" level of alcohol consumption and drinking just a small amount may in fact increase the risk of some cancers.

总体来看,6个队列研究所包括的35,132人中,有1,718人在研究期间罹患冠心病,其中有325人病情严重。冠心病发病率在曾经饮酒但已戒酒的人群中最高,达到6.1%,其中1.2%为严重病例;在规律重度饮酒者中最低,为3.8%,其中0.6%为严重病例。作者提醒,由于参与研究的重度饮酒者较少,尤其是女性重度饮酒者,因此重度饮酒者的冠心病发病率存在很大的疑问。

此次对酒精危害的重新评估始于2012年,其评估结果将与近期的其他研究结果呼应。其他研究也认为,偶尔饮酒也可能引发未来的健康问题。

Background

这将是二十年来饮酒指南的首次大逆转。报道称,医生将在新的饮酒指南中告诫民众:没有所谓的饮酒量“安全线”,小酌也可能增加患上某些癌症的风险。

最近发表在BMC Medicine上的一项基于35,132人数据的研究发现,无规律的饮酒会让心血管疾病的风险升高,但符合健康指南推荐量、规律适度的饮酒却可能对心血管有保护作用。

该报告称,你想通过饮酒获得的所谓益处,其实可以轻松地通过锻炼和健康饮食实现。

适度且规律的饮酒者,心脏病风险更低

导读:红酒并不像大家此前认为的那样对健康有益,事实情况恰恰相反。这将是二十年来饮酒指南的首次大逆转。

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